Estriol is the generic name of estriol in American English and its INN , USP , BAN , DCF , and JAN .     It is pronounced / ˌ ɛ s t r aɪ oʊ l / ES - TRYE -ohl . [ citation needed ] Estriolo is the name of estriol in Italian  and estriolum is its name in Latin , whereas its name remains unchanged as estriol in Spanish , Portuguese , French , and German .   Oestriol , in which the "O" is silent, was the former BAN of estriol and its name in British English ,    but the spelling was eventually changed to estriol . 
In a landmark paper, Liggins and Howie showed that a single course of antenatal corticosteroid therapy administered to women at risk for preterm delivery (PTD) reduced the incidence and severity of respiratory distress syndrome (RDS) and mortality in offspring [ 1 ]. Over two dozen randomized trials have confirmed these findings [ 2 ]. Subsequent trials have also shown that antenatal corticosteroid therapy improves circulatory stability in preterm neonates, resulting in lower rates of intraventricular hemorrhage (IVH) and necrotizing enterocolitis compared with unexposed preterm neonates.
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