Standard treatment for ulcerative colitis depends on the extent of involvement and disease severity. The goal is to induce remission initially with medications, followed by the administration of maintenance medications to prevent a relapse. The concept of induction of remission and maintenance of remission is very important. The medications used to induce and maintain a remission somewhat overlap, but the treatments are different. Physicians first direct treatment to inducing remission, which involves relief of symptoms and mucosal healing of the colon's lining, and then longer term treatment to maintain remission and prevent complications. Acute severe ulcerative colitis requires hospitalisation, exclusion of infections, and corticosteroids . 
Next came a one-sided bout against heavy underdog Gary "Big Daddy" Goodridge at Pride Total Elimination 2003 .  Emelianenko took down Goodridge after wobbling him with standing combinations, then finished him with ground and pound in the first round by referee stoppage. Emelianenko broke his hand in this fight, resulting in surgery.  He has since reinjured this hand, leading to several postponed bouts.  In 2011, Goodridge recalled his fight with Emelianenko; "Fedor hits so hard, I don't remember anything (from the fight). No one has his speed and power combo. He fought for 10 years at the top. He doesn't owe anything else to the sport." 
Mehling LM, Piper T, Dib J, Pedersen DS, Madea B, Hess C, Thevis M. Development and validation of a HPLC–QTOF-MS method for the determination of GHB-?-O-glucuronide and GHB-4-sulfate in plasma and urine. Forensic Toxicol (2016). doi:/s11419-016-0339-4
Mora-Rodriguez, R.; Ortega, .; Fernandez-Elias, .; Kapsokefalou, M.; Malisova, O.; Athanasatou, A.; Husemann, M.; Domnik, K.; Braun, H. Influence of Physical Activity and Ambient Temperature on Hydration: The European Hydration Research Study (EHRS). Nutrients 2016, 8, 252.