When used in high doses, a small amount of the medication is absorbed into the bloodstream and some side effects beyond the mouth and throat may develop. The most likely to be encountered are easy bruisability of the skin and suppression of the adrenal glands. The significance of adrenal gland suppression is discussed in further detail in the pamphlet entitled Asthma and Steroids in Tablet Form , prepared by the Partners Asthma Center. The risk from the long-term use of inhaled steroids in terms of hastening thinning of the bones (osteoporosis) is currently being studied. However, it is widely agreed that any risk that may be discovered will be far less than that resulting from use of steroids in tablet form in doses needed to achieve the same control of asthma.
In 4-6 years old asthmatic children, the systemic availability of budesonide following administration of Budesonide Nebuliser Suspension via a jet nebuliser (Pari LC Jet Plus® with Pari Master® compressor) is approximately 6% of the nominal dose and 26% of the dose delivered to the patients. The systemic availability in children is about half of that in healthy adults. The maximal plasma concentration, occurring approximately 20 min after start of nebulisation is approximately nmol/L in 4-6 years old asthmatic children after a 1 mg dose. The exposure (Cmax and AUC) of budesonide following administration of a single 1 mg dose by nebulisation to 4-6 year old children is comparable to that in healthy adults given the same delivered dose by the same nebuliser system.
Hi, I just git over a month bout with swine flu, I was healthy feeling for about one week then ended up with a severe sore throat, bad headache that lasts for days, tight head, stuffy nose, chest congestion. I just finished a 10 day cycle of 2 antibiotics about 2 weeks ago. This new sickness has been going on for 9 days now, my throat, headaches etc…have subsided to be minor & manageable, but for the last 3 days I am up all night coughing really hard for hours & hours & about every 10-20 seconds. It is brought on at the end of my breathing in & the end of my breathing out. Once I get to the end of my breaths I have this very urgent feeling to cough (its an irritated, itch feeling) I am keeping my family awake & actually occasionally throw up while coughing so hard. We just moved from the city to the country a few months ago, the air is very dry feeling, I have about 5+ acres of scotch broom right next to my house (we have a guy in the process of cutting it all down) Ive never known myself to have allergies & actually grew up on a ranch with many acres of scotch with no symptoms. I just turned 29 & yes I do smoke & have been for about 14yrs. I am quitting & have no desire to smoke anymore. I dont drink. I know I have some sorta sickness (probably viral) without having to go to an expensive doctor is there any common store bought product thats I can get that will relieve this annoying irritation & itch. My family & I need sleep & this is affecting my days as I have to stay home because the coughing is too often & too much. Thanks for reading this & thanks in advance for your help!