I would imagine taking doses at equal times apart would allow for the drugs to work properly. As if you took a this drug with only say 4 hours to your next usual suppose dose it would mean for a while extra strain for your body to adjust, probably near to double the dose. So spacing them out equally would be beneficial and also you can remember when your next dose is or would be due. I would say a drug taken 4 times a day would benefit from 6 hours apart equally not 3-4 hours just to get them in before bed and not to disturb sleep. You should be taking better care of yourself so if it means to have nap in the day because of night waking medication. You must.
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